International Journal of Head and Neck Surgery

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VOLUME 1 , ISSUE 2 ( May-August, 2010 ) > List of Articles

RESEARCH ARTICLE

Treatment Intensification in the ‘High-risk’ Individual

Prathamesh S Pai

Citation Information : Pai PS. Treatment Intensification in the ‘High-risk’ Individual. Int J Head Neck Surg 2010; 1 (2):93-96.

DOI: 10.5005/jp-journals-10001-1016

Published Online: 00-08-2010

Copyright Statement:  Copyright © 2010; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

The high-risk individual merits treatment intensification. However, there are concerns with CERT. More supportive care is necessary as toxicity is higher. Treatment related death is a reality. Hence before we set out to prescribe concurrent chemoradiation we would need to stratify them according to the risk factors, their performance status and bear in mind the costs involved in intensive support during treatment.

Apart from chemoradiation we need to explore emerging treatment strategies such as fractionated radiation therapy, and targeted therapies such as epidermal growth factor receptor blockade which might offer better if not similar results but with lesser toxicity.


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