International Journal of Head and Neck Surgery

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VOLUME 1 , ISSUE 2 ( May-August, 2010 ) > List of Articles


Papillary Thyroid Carcinoma with Malignant Pleural Effusion: Dilemma of Etiology

Arvind Krishnamurthy, KT Siddappa

Citation Information : Krishnamurthy A, Siddappa K. Papillary Thyroid Carcinoma with Malignant Pleural Effusion: Dilemma of Etiology. Int J Head Neck Surg 2010; 1 (2):117-119.

DOI: 10.5005/jp-journals-10001-1023

Published Online: 01-12-2011

Copyright Statement:  Copyright © 2010; The Author(s).


Papillary carcinomas of thyroid generally have an indolent course with metastatic disease in less than 5% of patients. Common sites of distant metastasis include lung and bone. A presentation with malignant pleural effusion is exceedingly rare with only a handful of cases reported in literature. We present a case and discuss the treatment of a patient presenting of papillary thyroid cancer with a relapse of the disease in the pleural cavity. There are no standard treatment recommendations in this setting in view of paucity of published data from literature.

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  1. The malignant pleural effusion: A review of cytopathologic diagnoses of 584 specimens from 472 consecutive patients. Cancer 1985;56(4):905-09.
  2. Pleural effusion in patients with differentiated papillary thyroid cancer. South Med J 1994;87(11):1111-16.
  3. Differentiated thyroid cancer presenting initially with distant metastasis. Am J Surg 1997;174:474-76.
  4. Papillary thyroid cancer with malignant pleural effusion. Tuberculosis and Respiratory Diseases Apr. 2008;64(4).
  5. Pleural effusion resulting from metastatic papillary carcinoma of the thyroid. Chest 1992;101:1448-50.
  6. Hürthle cell carcinoma of the thyroid with contralateral malignant pleural effusion. Onkologie 2009;32:47-49.
  7. Albert Einstein Medical Center, Philadelphia. Papillary carcinoma of thyroid recurring as pleural effusion after 26 years after curative therapy. Chest 2006;130(4):331S.
  8. Variables predicting distant metastases in thyroid cancer. Laryngoscope 2005;15:661-67.
  9. Different features of pulmonary metastases in differentiated thyroid cancer: Natural history and multivariate statistical analysis of prognostic variables. J Nucl Med 1993;34:1626-31.
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