International Journal of Head and Neck Surgery

Register      Login

VOLUME 11 , ISSUE 1 ( January-March, 2020 ) > List of Articles

CASE REPORT

Metastatic Hepatocellular Carcinoma Presenting as Maxillary Sinus Lesion

KG Somashekara, Lakshmi Shantharam, GM Bilkhis Mahjabeen

Keywords : Maxillary sinus, Metastasis,Hepatocellular carcinoma

Citation Information : Somashekara K, Shantharam L, Mahjabeen GB. Metastatic Hepatocellular Carcinoma Presenting as Maxillary Sinus Lesion. Int J Head Neck Surg 2020; 11 (1):19-21.

DOI: 10.5005/jp-journals-10001-1345

License: CC BY-NC 4.0

Published Online: 00-03-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Metastasis of malignant tumors to the sinonasal area is an infrequent occurrence and usually indicates the late stage of the primary disease. We report a rare case of previously undiagnosed metastatic hepatocellular carcinoma presenting solely as a maxillary sinus lesion. We have also reviewed literature on hepatocellular carcinoma metastasizing to the sinonasal area and discussed the pathogenesis of the possible routes of metastatic spread.


PDF Share
  1. Liu CY, Chang LC, et al. Metastatic hepatocellular carcinoma to the nasal cavity: A case report and review of literature. J Cancer Sci Ther 2011;3:081–083. DOI: 10.4172/1948-5956.1000064.
  2. Carrau RL, Myers EN. Neoplasms of the nose and paranasal sinuses. In: Bailey BJ, Calhoun KH, et al. ed: Head and Neck Surgery – Otolaryngology, 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2001. pp. 1247–1264.
  3. Bernstein JM, Montgomery WM, et al. Metastatic tumours of the maxilla, nose and paranasal sinuses. Laryngoscope 1966;76:621–650. DOI: 10.1288/00005537-196604000-00003.
  4. Nahum AM, Bailey BJ. Malignant tumours metastatic to the paranasal sinuses: Case report and review of the literature. Laryngoscope 1963;73:942–953. DOI: 10.1288/00005537-196307000-00009.
  5. Lin CD, Cheng KS, et al. Metastatic hepatocellular carcinoma in the nasal septum: report of a case. J Formos Med Assoc 2002;101(10):715–718.
  6. Kim HS, Shin JW, et al. Metastasis of hepatocellular carcinoma to the small bowel manifested by intussusception. World J Gastroenterol 2006;12(12):1969–1971. DOI: 10.3748/wjg.v12.i12.1969.
  7. Huang H-H, Chang P-H, et al. Sinonasal metastatic hepatocellular carcinoma. Am J Otolaryngol 2007;28:238–241. DOI: 10.1016/j.amjoto.2006.08.012.
  8. Kolarevic D, Tomasevic Z, et al. Metastasis of hepatocellular carcinoma presented as a tumour of the maxillary sinus and retrobulbar tumour. Vojnosanit Pregl 2011;68(4):359–362. DOI: 10.2298/VSP1104359K.
  9. Aung TH, Po YC, et al. Hepatocellular carcinoma with metastasis to the skull base, pituitary gland, sphenoid sinus and cavernous sinus. Hong komg Med J 2002 Feb;8(1):48–51.
  10. Okada H, Kamino Y, et al. Metastatic hepatocellular carcinoma of maxillary sinus: A rare autopsy case without lung metastasis and a review. Int J. Oral Maxillofacial Surg 2003;32:97–100. DOI: 10.1054/ijom.2002.0242.
  11. Hwang CS, Kim YS, et al. A case of extrahepatic metastasis of Hepatocellular carcinoma in nasal septum managed with endoscopic resection. J Rhinol 2012;19(1):74–76.
  12. Matsuda H, Tanigaki Y, et al. A case of metastatic hepatocellular carcinoma in the nasal cavity. Eur Arch Otorhinolaryngol 2005;263:305–307. DOI: 10.1007/s00405-005-1000-8.
  13. Tandon S, Nair A, et al. Hepatocellular carcinoma presenting as an isolated sphenoid sinus lesion. Ear Nose throat J 2012 Jan;91(1):E10–E13. DOI: 10.1177/014556131209100116.
  14. Chang CW, Wang TE, et al. Unusual presentation of metastatic hepatocellular carcinoma in the nasal septum. A case report and review of the literature. Med Oncol 2008;25:264–268. DOI: 10.1007/s12032-007-9028-9.
  15. Kourelis K, Chen T, et al. Metastatic hepatoma of maxillary sinus with atypical presentation. ANZ J Surg 2012;82:555–557.
  16. Satake N, Yoshida S, et al. Adenoid cystic carcinoma of maxillary sinus with metastatic hepatocellular carcinoma. APMIS 2005;113:450–455. DOI: 10.1111/j.1600-0463.2005.apm_137.x.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.