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VOLUME 11 , ISSUE 3 ( July-September, 2020 ) > List of Articles
Annanya Soni, Amit Kumar Gupta
Keywords : Caspofungin, L. amphotericin-B, Posaconazole, Sinonasal mucormycosis
Citation Information : Soni A, Gupta AK. Sinonasal Mucormycosis in a Tertiary Care Center: A Review of 30 Cases. Int J Head Neck Surg 2020; 11 (3):55-57.
License: CC BY-NC 4.0
Published Online: 05-11-2020
Copyright Statement: Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.
Aim and objective: To report our experience in presentation, treatment, and outcome of rhino-orbito-cerebral mucormycosis in our institute. Materials and methods: Retrospective, noncomparative analysis of medical records of 30 patients with mucormycosis seen over a period of 5 years. Results: Data of 30 patients, 22 males and 8 females with a mean age of 47.3 (range 25–70 years), were analyzed. Total 25 patients had diabetes mellitus, 3 were post-renal transplant, and 2 were post-bone marrow transplant and on immunosuppressive drugs. Ophthalmic signs and symptoms were present in 12 patients, and intracranial involvement was present in 11 patients. Computed tomography/magnetic resonance imaging (CT/MRI) revealed involvement of paranasal sinuses in all patients. All were treated with amphotericin-B (3–7 g) and 29 patients underwent appropriate surgery. Posaconazole/caspofungin was started as adjuvant treatment in certain cases. Conclusion: Mucormycosis is a rapidly spreading fungal disease with high mortality and demands immediate management without delay and generous debridement.
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