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VOLUME 11 , ISSUE 4 ( October-December, 2020 ) > List of Articles
Usha Agrawal, Manveen Kaur, Varsha Narula
Keywords : Sarcomatoid, Squamous cell carcinoma,Carcinosarcoma
Citation Information : Agrawal U, Kaur M, Narula V. Sarcomatoid Carcinoma of Tongue: A Case Report. Int J Head Neck Surg 2020; 11 (4):75-77.
License: CC BY-NC 4.0
Published Online: 08-12-2020
Copyright Statement: Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.
Sarcomatoid carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is a biphasic tumor consisting of epithelial and mesenchymal components. The diagnosis often presents a clinicopathological challenge solved only by immunohistochemistry. Because of different behavior and treatment response, there is a need to diagnose this entity accurately for better management and therapeutic intervention. In the present article, we report a case of SC of the tongue in a 65-year-old male who presented with a polypoidal growth over the lateral border of his tongue with a short history of 1 month. Immunohistochemical expression of cytokeratin was strongly positive in the epithelial component and focally in the spindle cell component. The spindle cell component showed a strong positivity for vimentin.
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