International Journal of Head and Neck Surgery

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VOLUME 11 , ISSUE 4 ( October-December, 2020 ) > List of Articles


Primary Lymphoma of Thyroid: A Diagnostic Dilemma

Namita Bhutani, Rajnish Kalra, Monika Sangwan, Sumiti Gupta, Ramesh Lamba

Citation Information : Bhutani N, Kalra R, Sangwan M, Gupta S, Lamba R. Primary Lymphoma of Thyroid: A Diagnostic Dilemma. Int J Head Neck Surg 2020; 11 (4):84-87.

DOI: 10.5005/jp-journals-10001-1398

License: CC BY-NC 4.0

Published Online: 28-09-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Primary thyroid lymphoma (PTL) is a rarely encountered clinical entity that occurs in late age intrinsically associated with Hashimoto's thyroiditis, comprising of 0.6–5% of thyroid cancers in most series. We present a case of B-cell origin thyroid lymphoma. The diagnosis was made by combined histology and immunochemistry. A 60-year-old woman presented with an enlarging neck mass with odynophagia. On admission, the sonogram of the thyroid gland showed an enlarged mass and computed tomography scan demonstrated diffuse enlargement of the thyroid. The histological investigation revealed the presence of a diffuse large B-cell non-Hodgkin's lymphoma. The patient underwent chemotherapy. Clinicians should include PTL in the differential diagnosis of a rapidly enlarging thyroid mass. Thyroid ultrasound and fine-needle aspiration cytology, using flow cytometry and immunohistochemistry, remain the main modalities used to confirm the presence of lymphoma. The prognosis is generally excellent but can be varied because of the heterogeneous nature of thyroid lymphomas. Despite its rarity, PTL should be promptly recognized because its management is quite different from the treatment of other neoplasms of the thyroid gland.

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