International Journal of Head and Neck Surgery

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VOLUME 2 , ISSUE 1 ( January-April, 2011 ) > List of Articles


Spontaneous Small Bowel Perforations in Patients Receiving Radiotherapy or Chemotherapy for Advanced Head and Neck Cancer

Muttagi Sidramesh, Pankaj Chaturvedi

Citation Information : Sidramesh M, Chaturvedi P. Spontaneous Small Bowel Perforations in Patients Receiving Radiotherapy or Chemotherapy for Advanced Head and Neck Cancer. Int J Head Neck Surg 2011; 2 (1):67-68.

DOI: 10.5005/jp-journals-10001-1052

Published Online: 01-08-2012

Copyright Statement:  Copyright © 2011; The Author(s).


Gastroduodenal perforations are known to occur due to various causes. However, such problems involving small bowel and manifesting spontaneously, especially in a head and neck cancer patient, undergoing chemoradiation has never been described in the literature. We report three cases of head and neck cancer that were undergoing treatment (one case curative and two cases palliative), during which small bowel perforation manifested requiring urgent surgical intervention. We seek to highlight this problem, so as to ascertain the possible mechanisms of its causation, identify a group of patients at risk, evolve possible preventive strategies and facilitate earlier diagnosis and treatment.

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  1. Gastroduodenal perforation in cancer patients. Hepatogastroenterology Sep-Oct 1999; 46(29):2878-81.
  2. Spontaneous gastrointestinal perforation in patients with lymphoma receiving chemotherapy and steroids: Report of three cases. Nippon Ika Daigaku Zasshi Feb 1999;66(1):37-40.
  3. Spontaneous free perforation of the small intestine. Dis Colon Rectum May 1983;26(5):323-26.
  4. Perforation of small intestine during hematologic recovery in an elderly man after induction therapy for acute lymphoblastic leukemia L3. Rinsho Ketsueki Feb 2000;41(2):146-51.
  5. Small-bowel perforation secondary to metastatic carcinoma of the breast. Am Surg Apr 1998;64(4):312.
  6. Emergency abdominal surgery for small bowel perforation secondary to metastatic lung cancer. Tohoku J Exp Med Jul 1999;188(3):265-70.
  7. Multiple spontaneous small bowel perforations due to systemic cholesterol atheromatous embolism. Intern Med Jul 1999;38(7):580-84.
  8. Multiple spontaneous intestinal perforations from atheroembolism after thrombolytic therapy: A case report. Can J Surg Aug 1994;37(4):325-28.
  9. Crystalglobulin-induced vasculopathy accompanying ischemic intestinal lesions of a patient with myeloma. Pathol Int Feb 1996;46(2):165-70.
  10. Vasculitic small bowel perforation masquerading as spontaneous bacterial peritonitis in a patient with decompensated liver disease. Eur J Gastroenterol Hepatol Apr 1999;11(4):459-61.
  11. Nonsteroidal anti-inflammatory drug enteropathy. Gastrointest Endosc Clin N Am Jan 1999;9 (1):125-33.
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