International Journal of Head and Neck Surgery

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VOLUME 4 , ISSUE 3 ( September-December, 2013 ) > List of Articles


Study of Cytodiagnosis of Head and Neck Neoplastic Lesions and Comparison with Histopathology

Maniyar U Amit, Harshid Laxmanbhai Patel, BH Parmar

Citation Information : Amit MU, Patel HL, Parmar B. Study of Cytodiagnosis of Head and Neck Neoplastic Lesions and Comparison with Histopathology. Int J Head Neck Surg 2013; 4 (3):119-122.

DOI: 10.5005/jp-journals-10001-1157

Published Online: 01-03-2015

Copyright Statement:  Copyright © 2013; The Author(s).



The development of aspiration cytology is one of the biggest advances in anatomic pathology. Cancer has become one of the 10 leading causes of death in India. Head and neck neoplasia is a major form of cancer in India, accounting for 23% of all cancers in males and 6% in females. The advantages of fine needle aspiration cytology (FNAC) are: it is safe, sensitive and specific for the diagnosis of malignancy, gives a rapid report, requires little equipment, causes minimal discomfort to the patient, is an out patient procedure, repeatable and cost effective avoids the use of frozen section, reduces the rate of exploratory procedures and allows a definitive diagnosis of inoperable cases. FNAC is of particular relevance in head and neck lesions because of easy assessibility, excellent patient compliance, minimally invasive nature of procedure and helping to avoid surgery in non-neoplastic lesions, inflammatory conditions and also some tumors.

Aims and objectives

To test the utility of FNAC, to establish the diagnostic accuracy of cytology by comparison with histopathology diagnosis and to establish the sensitivity and specificity of this technique in head and neck neoplastic lesion.

Materials and methods

The present study was undertaken in the Department of Pathology, Government Medical College and Hospital, Nashik, between January 2008 and June 2009.


In the present study, maximum number of aspirates from head and neck neoplastic lesions were found to be of lymph nodes (56.37%). Of the total 378 cases, 71.69% were malignant. 6th decade was the most common age group affected (26.46%). Mean age group was found to be 45.84 years. Males were more commonly affected (65.34%). The male to female ratio was 1.8:1. Out of 92 cases available for follow-up, 85.87% of the cases were same as histopathological diagnosis.

Summary and conclusion

Excisional biopsy remains the gold standard for diagnosis of head and neck neoplastic lesion, cytological study can establish the diagnosis of the majority of head and neck neoplastic lesions and can be recommended as an adjunct to histopathology.

How to cite this article

Amit MU, Patel HL, Parmar BH. Study of Cytodiagnosis of Head and Neck Neoplastic Lesions and Comparison with Histopathology. Int J Head Neck Surg 2013; 4(3):119-122.

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  1. Differential diagnosis of neck masses. In: Cummings CW, Flint PW, Harkar LA (Eds). Cummings Otolaryngology Head and Neck Surgery (4th ed). Mosby: Elsevier 2005:2542.
  2. Cytology in the otorhino-laryngologists domain: A study of 150 cases, emphasizing diagnostic utility and pitfalls. Ind J Otolarnyngol Head Neck Surg 2002;54(2):107-10.
  3. Biopsy of needle puncture and aspiration. Ann Surg 1930;92:169-81.
  4. Fine needle aspiration biopsy. An analysis of 89 head and neck cases. J Oral Maxillofac Surg 1990;48:702-06.
  5. Fine needle aspiration of neck masses. Available from:
  6. Stell and Maran's Head and Neck Surgery (4th ed). Oxford: Butterworth Heinemann 2000:p21.
  7. Diagnostic cytopathology (2nd ed). London: Churchill Livingstone; 2003:6.
  8. National Cancer Control Programme: Current status and strategies. In: Agarwal SP (Ed). Fifty years of cancer control in India. Dir Gen of Health Services, MOHFW, Government of India 2002;41-47.
  9. Spectrum of head and neck cancers at Allahabad. J Otolaryngol Head Neck Surg 2001;53:16-20.
  10. Trends of prevalence and pathological spectrum of head and neck cancers in North India. Indian J Cancer 2005;42:89-93.
  11. Fine needle aspiration cytology: Diagnostic principles and dilemmas. J Clin Pathol 2007;60(3):335-36.
  12. Fine needle aspiration biopsy. Laryngoscope 2001;111(9):1551-57.
  13. Silverberg's principles and practice of surgical pathology and cytopathology (4th ed). NY: Churchill Livingstone-Elsevier; 2006;22.
  14. Cystic lesions of the head and neck: Cytohistological correlation in 63 cases. Cytopathology 2007;18(3):184-90.
  15. Fine needle aspiration cytology: The Auckland experience. Aust N Z J Surg 1992 May;62(5):368-72.
  16. Efficacy and cost-effectiveness of multihole fine-needle aspiration of head and neck masses. Laryngoscope 1997 Jun;107(6):759-64.
  17. Fine needle aspiration cytology of head and neck masses. Seven years’ experience in a secondary care hospital. Acta Cytol 2003;47(3): 387-92.
  18. Role of repeat fine needle aspiration cytology in head and neck lesions: Preliminary study. J Laryngol Otol 2004;118(4):294-98.
  19. The role of operator experience in fine needle aspiration cytology of head and neck masses. Int J Oral Maxillofac Surg 1999;28:441-44.
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