International Journal of Head and Neck Surgery

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VOLUME 1 , ISSUE 3 ( September-December, 2010 ) > List of Articles

CASE REPORT

Cancrum Oris-associated with Acute Myeloid Leukemia: A Forgotten Disease

Arvind Krishnamurthy, Shirley Sundersingh, Satish Srinivas, Anita Vaidhyanathan, Krishnarathinam

Citation Information : Krishnamurthy A, Sundersingh S, Srinivas S, Vaidhyanathan A, K. Cancrum Oris-associated with Acute Myeloid Leukemia: A Forgotten Disease. Int J Head Neck Surg 2010; 1 (3):167-169.

DOI: 10.5005/jp-journals-10001-1032

Published Online: 01-04-2012

Copyright Statement:  Copyright © 2010; The Author(s).


Abstract

Cancrum oris is an orofacial gangrene, which during its fulminating course causes, progressive and mutilating destruction of the infected tissues with a consortium of microorganisms. This condition is considered to represent the “face of poverty” because factors connected with poverty, such as chronic malnutrition, poor oral hygiene and sanitation, faecal contamination, and exposure to viral and bacterial infections in an immunosupressed host contribute to disease progression. This condition is seen almost exclusively among the young children and carries a high mortality rate.

We present a case of cancrum oris in a 45 years old lady being treated for acute myeloid leukemia with chemotherapy, who in addition to a polymicrobial bacterial infection had superinfection with Mucormycosis.


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  1. Cancrum oris-like lesion associated with acute myelogenous leukemia. Oral Surg Oral Med Oral Pathol Jul 1974;38(1):10-14.
  2. Noma: A forgotten disease. Dent Clin North Am 2003;47(3):559-74.
  3. Noma: A review. Ann Plast Surg 1996;37:657-68.
  4. Cancrum oris: Its incidence and treatment in Enugu, Nigeria. Br J Oral Maxillofac Surg 2002;40(5):406-09.
  5. A history of noma, the “Face of Poverty.” Plast Reconstr Surg 2003;111(5):1702-07.
  6. Isolation of Fusobacterium necrophorum from cancrum oris (noma). Am J Trop Med Hyg 1999;60(1):150-56.
  7. Enwonwu CO, Idigbe EO. Microbial understanding and mysteries of noma (cancrum oris). Oral Dis 1999;5(2):150-55.
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