International Journal of Head and Neck Surgery

Register      Login

VOLUME 12 , ISSUE 3 ( July-September, 2021 ) > List of Articles

CASE REPORT

Ectopic Sebaceous Glands over Buccal Mucosa: A Case Report on Fordyce Spot

Prajakta M Bapat, Uma P Chaturvedi, Sujaya Mazumder, Raji Naidu, Susan Cherian

Keywords : Ectopic sebaceous glands, Fordyce granules, Hereditary nonpolyposis colorectal cancer

Citation Information : Bapat PM, Chaturvedi UP, Mazumder S, Naidu R, Cherian S. Ectopic Sebaceous Glands over Buccal Mucosa: A Case Report on Fordyce Spot. Int J Head Neck Surg 2021; 12 (3):119-120.

DOI: 10.5005/jp-journals-10001-1444

License: CC BY-NC 4.0

Published Online: 17-12-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Aim and objective: To highlight the importance of histopathological diagnosis to identify Fordyce spots. Background: These are normal variants in which sebaceous glands are ectopically located over the mucosal surfaces and are not in association with hair follicles. Fordyce spots, or Fordyce granules, can be found on the genital mucosa (glans penis and labia minor), esophagus, gastroesophageal junction, uterine cervix, sole of the foot, thymus, and tongue. Case description: The following two cases are included in our case report: (1) A 30-year-old male patient with a lesion of size 2 mm in diameter, located over right buccal mucosa. This was a painless white patch, clinically suggestive of lichen planus. This was histopathologically confirmed as Fordyce spots. (2) This case was an incidental finding along with erythroplakic patch in a 60-year-old man. Conclusion: Histopathology is the gold standard of diagnosis in this condition; it is imperative for the pathologist to identify the presence of Fordyce spots. Clinical significance: Fordyce spots over the oral mucosa are reported rarely and is known to have an array of clinical mimics such as malignancies of oral mucosa.


HTML PDF Share
  1. Fordyce JA. A peculiar affection of the mucous membrane of the lips and oral cavity. J Cutan Dis 1896;14:413–419. DOI: 10.1001/archderm.1996.03890350023003
  2. Braun-Falco O, Plewig G, Wolff HH, et al. Diseases of the lips and oral mucosa. In Dermatology (pp. 1164–1165). Berlin, Heidelberg: Springer; 2000. DOI: 10.1007/978-3-642-97931-6_33
  3. Mattoo KA, Singh M, Gupta S. Fordyce granules associated with hypopigmentation of facial skin. Oral Surg, Oral Med, Oral Radiol 2014;2:23–24. DOI: 10.1007/978-3-642-97931-6_33
  4. Baeder FM, Pelino JE, De Almeida ER, et al. High-power diode laser use on Fordyce granule excision: a case report. J Cosmet Dermatol 2010;9(4):321–324. DOI: 10.1111/j.1473-2165.2010.00531.x
  5. Hoque T, Islam AM. Fordyce's disease treated with pimacrolimus: a rare case report. Anwer Khan Modern Med Coll J 2018;9(2):148–151. DOI: 10.3329/akmmcj.v9i2.39212
  6. Almeida FT, Gomes RR, Leite AF, et al. Oral manifestations of hereditary nonpolyposis colorectal cancer syndrome: a family case series. J Med Case Rep 2014;8(1):1–6. DOI: 10.1186/1752-1947-8-249
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.