Clear cell, Locally aggressive, Odontogenic carcinoma, Surgery
Citation Information :
Thiagarajan S, Babu S, Nandini H, Kavitha K. Clear Cell Odontogenic Carcinoma of the Mandible: Diagnostic Difficulty and Therapeutic Dilemma. Int J Head Neck Surg 2017; 8 (3):118-120.
Clear cell odontogenic carcinoma (CCOC) is a rare tumor commonly involving the mandible, in elderly women. It is locally aggressive with a tendency to spread to lymph nodes and also has distant metastasis. Until date, only about 100 cases have been reported in the literature. Here, we report one such case in a 60-year-old lady who presented with a nonhealing ulcer of the oral cavity following a tooth extraction. She underwent surgery followed by adjuvant radiotherapy and is on follow-up for over 6 months, free of disease. The CCOC must be considered as one of the differential diagnosis in tumors involving the jaw with a radiolucent lesion as seen on an orthopantomogram (OPG) and clear cell component histopathologically. We have also done a literature review of the reports published so far and the best possible treatment options have been discussed in the light of these evidences.
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