Sleep disorders are an increasingly important and relevant burden faced by society, impacting at the individual, community and global level. Varied presentations and lack of awareness can make accurate and timely diagnosis a challenge. Early recognition and appropriate intervention are a priority. The key characteristics, clinical presentations and management strategies of common sleep disorders such as circadian rhythm disorders, restless legs syndrome, REM behavior disorder, hypersomnia and insomnia are outlined in this review.
M Zucconi, R Ferri. Assessment of sleep disorders and diagnostic procedures 1. Classification of sleep disorders, ESRS Sleep Medicine Textbook, Chapter B1, pp. 95–109.
Ebisawa T, Uchiyama M, et al. Association of structural polymorphisms in human period3 gene with delayed sleep phase syndrome. EMBO. 2001;2(4), 342–346.
Toh KL, Jones CR, et al. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science. 2001;291:1040.
Tamrat R, Huynh-Le MP, et al. Non-pharmacologic interventions to improve the sleep of hospitalized patients: a systematic review. J Gen Intern Med. 2014 May;29(5):788–795.
Restless legs syndrome; Ferre S, Garcia-Borreguero D. The Neuroscientist 2018.
Xie J, Chahal CAA, et al. Periodic limb movements of sleep are associated with an increased prevalence of atrial fibrillation in patients with mild sleep-disordered breathing..Int J Cardiol. 2017 Aug 15;241:200–204.
Stephany Fulda; Idiopathic REM sleep behavior disorder as a long-term predictor of neurodegenerative disorders EPMA J. 2011 Dec; 2(4): 451–458.
Hilker R, Burghaus L, et al. Functional brain imaging in combined motor and sleep disorders. J Neurol Sci. 2006;248:223–226.
Longstreth WT Jr, Koepsell TD, et al. The epidemiology of narcolepsy. Sleep. 2007 Jan;30(1):13–26.
Thomas Roth. Insomnia: Definition, Prevalence, Etiology, and Consequences; J Clin Sleep Med. 2007 Aug 15; 3(5 Suppl): S7–S10.
Evelyn Mai, MD and Daniel J Buysse, MD. Insomnia: Prevalence, Impact, Pathogenesis, Differential Diagnosis, and Evaluation Sleep Med Clin. 2008;3(2):167–174.