Background: This is a retrospective study of patients who underwent either outpatient department (OPD) clinic or operation theater (OT) procedures between January 2018 and December 2022. The study aims to analyze 5 years of data on the types of procedures performed in a tertiary care hospital in Central India. As the type of procedure is an indirect marker of the pattern of underlying diseases, the study will also determine the impact of COVID-19 waves on the variation of ear, nose, and throat (ENT) subsites involved. The four subsites defined were ear, nose, transoral oral cavity, and neck. Data were obtained from the medical records department, OT register, and OPD procedure register. Results: During this 5-year study period, 15,592 OPD clinic procedures and 3,202 OT complex procedures were performed. Among yearly OPD procedures, videolaryngoscopy (VLS) was common in the years 2018 and 2019, ear examination under microscope (EUM) was common in the year 2020, and diagnostic nasal endoscopy (DNE) was common in the years 2021 and 2022. In totality, the common OPD procedure performed was DNE (5,470) followed by VLS (3,968), EUM (3,368), clinical vertigo evaluation (1,018), and videonystagmography (VNG) (561). In 2018, 2019, 2020, and 2022, the common subsite for surgery was an ear, followed by the nose, transoral and oral cavity, and neck. However, in 2021, nasal surgeries predominated, followed by transoral and ear surgeries. In 5 years, tympanoplasty was the most common individual surgical procedure performed. Conclusion: In 2021, diagnostic nasal endoscopies and nasal surgeries predominated. This documents the unprecedented surge in cases of post-COVID-19 sinonasal mucormycosis. The data on OPD and surgical procedures in 2022 is comparable to pre-COVID-19 data for the years 2018–2019. This documents that we are presently having a similar disease scenario to pre-COVID-19 times.