International Journal of Head and Neck Surgery

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2012 | May-August | Volume 3 | Issue 2

EDITORIAL

Chris de Souza

Editorial

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:1] [Pages No:0 - 0]

PDF  |  DOI: 10.5005/ijhns-3-2-v  |  Open Access |  How to cite  | 

EDITORIAL

Editorial

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:1] [Pages No:0 - 0]

PDF  |  DOI: 10.5005/ijhns-3-2-vi  |  Open Access |  How to cite  | 

RESEARCH ARTICLE

Sudhir Naik, Sarika S Naik, S Ravishankara, Mohan K Appaji, MK Goutham, Nonthombam Pinky Devi, Annapurna S Mushannavar

Comparative Study of Intralesional Triamcinolone Acetonide and Hyaluronidase vs Placental Extract in 60 Cases of Oral Submucous Fibrosis

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:7] [Pages No:59 - 65]

PDF  |  DOI: 10.5005/jp-journals-10001-1096  |  Open Access |  How to cite  | 

Abstract

Background

Oral submucous fibrosis (OSMF) is a common premalignant condition caused by chewing arecanut, betel quid and gutkha with tobacco. Its medical treatment is not yet fully standardized, although the optimal doses of its medical treatment is in the form of triamcinolone acetonide combined with hyaluronidase or intralesional placental extract.

Objectives

We compared the efficacy of intralesional triamcinolone acetonide combined with hyaluronidase in group A vs placental extract in group B.

Design

Comparative case series analysis series study with random allocation of 60 patients equally into two groups.

Materials and methods

Patients of OSMF (60) were randomly allocated into two groups A and B. Group A (n = 30) patients received combination of triamcinolone acetonide (10 mg/ml) + hyaluronidase (1,500 IU) at weekly intervals for 8 weeks. Group B (n = 30) patients received 2 ml of placentrex injection intralesionally at weekly interval for 8 weeks. Treatment outcome was evaluated on the basis of improvement in trismus, oral mucosal pattern and reduction in burning sensation.

Results

Trismus improvements in group A with combination of triamcinolone acetonide + hyaluronidase were significantly better to that in group B where placentrex was used. No significant difference in results in the two groups were observed as far as improvement in oral mucosal pattern and burning sensation were compared in the two groups.

Conclusion

Combination of triamcinolone acetonide and hyaluronidase intralesionally is more effective than placental extract intralesionally in treatment of OSMF. But placental extract injections are cost-effective. No side effects were seen in both study groups.

How to cite this article

Naik SM, Appaji MK, Ravishankara S, Goutham MK, Devi NP, Mushannavar AS, Naik SS. Comparative Study of Intralesional Triamcinolone Acetonide and Hyaluronidase vs Placental Extract in 60 Cases of Oral Submucous Fibrosis. Int J Head Neck Surg 2012;3(2):59-65.

RESEARCH ARTICLE

Andrey Karpenko, Laslo Roman, Natalia Chumanikhina, Igor Kostyuk, Ramil Sibgatullin, Elena Belova, Nadezhda Evdokimova, Dilavar Dzhalilov

First Results of the Free Flap Transfer for the Head and Neck Reconstruction: The Public Hospital Experience

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:7] [Pages No:66 - 72]

PDF  |  DOI: 10.5005/jp-journals-10001-1097  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Karpenko A, Roman L, Chumanikhina N, Kostyuk I, Sibgatullin R, Belova E, Evdokimova N, Dzhalilov First Results of the Free Flap Transfer for the Head and Neck Reconstruction: The Public Hospital Experience. Int J Head Neck Surg 2012;3(2):66-72.

RESEARCH ARTICLE

Gurcharan Singh, Nikhil S Shetty

Multiple Pin Wheel Flaps and Its Modification in Special Areas of the Scalp

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:3] [Pages No:73 - 75]

PDF  |  DOI: 10.5005/jp-journals-10001-1098  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Singh G, Shetty NS. Multiple Pin Wheel Flaps and Its Modification in Special Areas of the Scalp. Int J Head Neck Surg 2012;3(2):73-75.

RESEARCH ARTICLE

Josena K Stephen, Kang Mei Chen, Veena Shah, Vanessa G Schweitzer, Glendon Gardner, Maria J Worsham, Shaleta Havard

Novel Dysregulated MicroRNAs in Primary Laryngeal Squamous Cell Cancer

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:6] [Pages No:76 - 81]

PDF  |  DOI: 10.5005/jp-journals-10001-1099  |  Open Access |  How to cite  | 

Abstract

Introduction

MicroRNAs (miRNAs) are endogenous, small, noncoding RNAs of 17 to 25 nucleotides that regulate approximately 30% of human genes. They are differentially expressed in various types of cancers compared with noncancerous tissues, suggesting that they may have crucial roles in tumorigenesis. The objective of this study was to identify laryngeal squamous cell cancer (LSCC)-specific miRNAs.

Materials and methods

A retrospective cohort of 10 LSCC and five normal laryngeal squamous epithelium samples were examined using a global miRNA profiling approach (HTG, Tucson, AZ, USA, 800 human miRNAs plus 10 endogenous control miRNAs). The expression status of selected dysregulated miRNAs that were significantly different from normal were verified by real-time quantitative PCR (qPCR).

Results

Twenty-three of the 800 human miRNAs had significantly different expression levels (p < 0.05) between LSCC and normal tissues. Fifteen of the 23 have not been previously reported in HNSCC and include: miR-663b, miR-663, miR-193b, miR-1291, miR-720, miR-191, miR-1224-3p, miR-214, miR- 1285, miR-1207-5p, miR-483-5p, miR-1225-3p, miR-1228, miR-1280 and miR-638. Consistently upregulated miR-31 and miR- 193b and differentially expressed miR-663b in LSCC were verified by qPCR.

Conclusion

The 15 novel miRNAs identified in this exploratory study, pending further confirmation and validation, may have clinical utility as LSCC-specific markers.

How to cite this article

Chen KM, Stephen JK, Havard S Shah V, Gardner G, Schweitzer VG, Worsham MJ. Novel Dysregulated MicroRNAs in Primary Laryngeal Squamous Cell Cancer. Int J Head Neck Surg 2012;3(2):76-81.

REVIEW ARTICLE

Jai Prakash Agarwal, Gunjan Baijal, Ranajit Kar

Radiation-Induced Xerostomia

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:5] [Pages No:82 - 86]

PDF  |  DOI: 10.5005/jp-journals-10001-1100  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Baijal G, Kar R, Agarwal JP. Radiation-Induced Xerostomia. Int J Head Neck Surg 2012;3(2): 82-86.

REVIEW ARTICLE

Seyed Amir Danesh-Sani

Clinical Photography for the Oral and Maxillofacial Surgery Practice

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:5] [Pages No:87 - 91]

PDF  |  DOI: 10.5005/jp-journals-10001-1101  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Danesh-Sani SA. Clinical Photography for the Oral and Maxillofacial Surgery Practice. Int J Head Neck Surg 2012;3(2):87-91.

REVIEW ARTICLE

Kiran Kumar, Devi Charan Shetty, Mahima Dua

Biopsy and Tissue Processing Artifacts in Oral Mucosal Tissues

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:7] [Pages No:92 - 98]

PDF  |  DOI: 10.5005/jp-journals-10001-1102  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Kumar K, Shetty DC, Dua M. Biopsy and Tissue Processing Artifacts in Oral Mucosal Tissues. Int J Head Neck Surg 2012;3(2):92-98.

CASE REPORT

Anil Poddar, Piyush Kedia

An Unusually Large Symptomatic Paratracheal Air Cyst

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:2] [Pages No:99 - 100]

PDF  |  DOI: 10.5005/jp-journals-10001-1103  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Poddar AK, Kedia P. An Unusually Large Symptomatic Paratracheal Air Cyst. Int J Head Neck Surg 2012;3(2):99-100.

CASE REPORT

Sudhir Naik, Sarika S Naik, S Ravishankara, Mohan K Appaji, MK Goutham, Nonthombam Pinky Devi, Annapurna S Mushannavar

Acute Accidental Formic Acid Poisoning: A Common Problem Reported in Rubber Plantations in Sullia

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:5] [Pages No:101 - 105]

PDF  |  DOI: 10.5005/jp-journals-10001-1104  |  Open Access |  How to cite  | 

Abstract

Background

Ingestion of formic acid, accidentally or with suicidal intention is a common problem among the workers in rubber plantations in Sullia. The diluted form of formic acid is used in coagulation of rubber latex. Sullia, a small town in South India, is well known for its rubber plantations. Easy accessibility to formic acid makes it susceptible to be used for committing suicide in this region. Also accidental ingestion are very common in these workers.

Aim:

To study a case report of accidental formic acid poisoning and its management.

Intervention

The patient was managed successfully by medical line of treatment. No gastric lavage or antidote was used in treatment and no vomiting induced. Nasogastric tube feeding was done and electrolyte imbalance was corrected.

Conclusion

Easy availability of formic acid should be curtailed by enforcing statutory limitations in its distribution and the complication of formic acid poisoning should be educated to these rubber workers. Patients with hematemesis or melena, after successful treatment, should be followed up with serial esophagogastroduodenoscopy for diagnosis and early treatment of strictures.

How to cite this article

Naik SM, Ravishankara S, Appaji MK, Goutham MK, Devi NP, Mushannavar AS, Naik SS. Acute Accidental Formic Acid Poisoning: A Common Problem Reported in Rubber Plantations in Sullia. Int J Head Neck Surg 2012;3(2):101-105.

CASE REPORT

Vijaykumar Goudappagouda Biradar

Ameloblastoma arising in Calcifying Odontogenic Cyst: A Rare Histologic Variant

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:2] [Pages No:106 - 107]

PDF  |  DOI: 10.5005/jp-journals-10001-1105  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Biradar VG. Ameloblastoma arising in Calcifying Odontogenic Cyst: A Rare Histologic Variant. Int J Head Neck Surg 2012;3(2):106-107.

CASE REPORT

Vladimir Bauer, Zorica Aleric, Ervin Jancic, Tatjana Bujas

Rare Tumors of the Neuroectodermal Origin: Report of Five Cases

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:4] [Pages No:108 - 111]

PDF  |  DOI: 10.5005/jp-journals-10001-1106  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Bauer V, Aleric Z, Jancic E, Bujas T. Rare Tumors of the Neuroectodermal Origin: Report of Five Cases. Int J Head Neck Surg 2012;3(2):108-111.

CASE REPORT

Priti Rakesh Dhoke, Sonali Prabhakar Khadakkar, Kanchan Sandeep Dhote, Samir Vijay Choudhary, Vivek Vishwas Harkare, Nudrat Parvez Kamal

Type III Second Branchial Cleft Cyst

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:3] [Pages No:112 - 114]

PDF  |  DOI: 10.5005/jp-journals-10001-1107  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Choudhary SV, Khadakkar SP, Harkare VV, Dhoke PR, Dhote KS, Kamal NP. Type III Second Branchial Cleft Cyst. Int J Head Neck Surg 2012;3(2):112-114.

CASE REPORT

Abbas Makarem, Nosrat Lotfi, Seyed Amir Danesh-Sani, Soudabeh Nazifi

Osteopetrosis: Oral and Maxillofacial Manifestations

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:3] [Pages No:115 - 117]

PDF  |  DOI: 10.5005/jp-journals-10001-1108  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Makarem A, Lotfi N, Danesh-Sani SA, Nazifi S. Osteopetrosis: Oral and Maxillofacial Manifestations. Int J Head Neck Surg 2012;3(2):115-117.

CASE REPORT

Khaja Naseeruddin

Schwannoma of Parapharyngeal Space

[Year:2012] [Month:May-August] [Volume:3] [Number:2] [Pages:3] [Pages No:118 - 120]

PDF  |  DOI: 10.5005/jp-journals-10001-1109  |  Open Access |  How to cite  | 

Abstract

How to cite this article

Naseeruddin K. Schwannoma of Parapharyngeal Space. Int J Head Neck Surg 2012;3(2): 118-120.

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