Oral squamous cell carcinoma, the fifth most common cancer worldwide, is a major cause of morbidity and mortality in India. It most commonly occurs in middle-aged and older individuals. Typically, they tend to be preceded by a premalignant state for a long time. The present study evaluates the clinicopathological profile of patients with oral lesions and the role of malpractices that promote carcinogenesis in the oral mucosa and the use of Ki-67 as an important predictor of the same.

The expression of Ki-67 was studied in paraffin-embedded tissue sections of oral lesions of all the cases after taking a detailed history and examination.

The study was conducted on 65 patients with 25 dysplastic and 40 malignant lesions. Males were affected more frequently than females. The most common age group affected was 31 to 60 years with mean age of 45.4 years. Anterior twothird of tongue (41%) was the most commonly affected site. 95% of the patients had a history of addiction in form of smoking, tobacco chewing and betel nut. Out of 25 cases of dysplasia, 11 showed low expression while out of 40 cases of squamous cell carcinoma only three showed low and 29 showed high expression of Ki-67.

The expression of Ki-67 correlates well with the disease progression from dysplasia to carcinoma of the oral cavity. It is therefore a marker of malignant transformation and carcinogenesis in oral premalignant lesions and in future it may serve as a prognostic tool in the early detection of malignancy.

Maheshwari V, Sharma SC, Narula V, Verma S, Jain A, Alam K. Prognostic and Predictive Impact of Ki-67 in Premalignant and Malignant Squamous Cell Lesions of Oral Cavity. Int J Head Neck Surg 2013;4(2):61-65.

Chauhan YS, Mukherji S. Intraosseous Hemangioma: A Case Report and Review of Literature. Int J Head Neck Surg 2013;4(2):66-69.

Ekhar VR, Mahore DM, Kapre GM, Bokare BD, Gawarle SH. Clinicopathological Study of Nonsquamous Cell Malignancies of the Head and Neck. Int J Head and Neck Surg 2013;4(2):70-73.

Rastogi V, Puri N, Mishra S, Arora S, Kaur G, Yadav L. An Insight to Oral Epithelial Dysplasia. Int J Head Neck Surg 2013;4(2):74-82.

Hussain R, Hassan U, Jamshed A, Loya A. Round Blue Cell Tumor arising in the Background of Ameloblastic Fibrosarcoma. Int J Head Neck Surg 2013;4(2): 83-85.

Jamshed A, Loya A, Tirmazi AH, Hussain R. Synovial Cell Sarcoma of the Hypopharynx. Int J Head Neck Surg 2013;4(2):86-88.

Mishra A, Jayalakshmi V, Chaturvedi UP, Chikhale NP, Patel RD, Cherian S. Oncocytic Variant of Papillary Thyroid Carcinoma and Associated Lymphocytic Thyroiditis: A Case Report with Review of Literature. Int J Head Neck Surg 2013;4(2):89-91.

Rout MR, Mohanty D, Bobba K, Meta C, Karri S. Presternal Thyroglossal Fistula: A Rare Case Report. Int J Head Neck Surg 2013;4(2):92-94.

Aggarwal P, Sohal BS, Uppal KS. Dentigerous Cyst of Mandible. Int J Head Neck Surg 2013; 4(2):95-97.

Divya GM, Hameed AS, Ramachandran K, Vinayak KV. Extraluminal Migration of Foreign Body: A Report of Two Cases. Int J Head Neck Surg 2013;4(2):98-101.

Vishak S, Sharma VK, Nilakantan A. Radioresistant Solitary Extramedullary Plasmacytoma of Larynx. Int J Head Neck Surg 2013;4(2):102-104.

Chauhan YS, Mukherji S. An Anatomical Variant: Low Lying Common Carotid Artery Bifurcation. Int J Head Neck Surg 2013;4(2):105-106.

Manekar VS, Chavan A. Retained Metallic Foreign Body in Cheek: A Diagnostic and Surgical Challenge. Int J Head Neck Surg 2013;4(2):107-109.

To emphasize that epiglottic cyst should be considered in the differential diagnosis of all adults presenting with stridor.

A 55-year-old male patient presented with stridor of 2 days duration. He also had complaints of gradually progressive difficulty in swallowing for solids and had muffled voice for the past 3 months. Oropharyngeal examination revealed a large cystic mass behind the base of tongue. An indirect laryngoscopy and 70° telescopic laryngoscopy showed a large cystic mass filling both vallecular regions obscuring rest of the larynx. He underwent tracheostomy for airway distress followed by excision of the cyst.

This case highlights the possibility of a rare presentation of epiglottic cyst in an adult presenting with stridor requiring an early definitive management.

Chandrakala S, Bhardwaj NS, Mohammadi K, Menon L. Stridor in Epiglottic Cyst: A Rare Presentation. Int J Head Neck Surg 2013;4(2):110-111.